Wrinkles form as a result of multiple changes in the skin that occur with aging, influenced by both internal (intrinsic) and external (extrinsic) factors. Here's a breakdown of what causes wrinkles over time:

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1. Loss of Collagen and Elastin

2. Thinning of the Skin Layers

3. Reduced Production of Natural Oils

4. Loss of Subcutaneous Fat

5. Repeated Facial Movements

6. Extrinsic Factors: Sun Exposure and Environmental Damage

7. Decreased Cell Turnover and Repair

8. Genetic Factors

9. Lifestyle Factors: Smoking, Diet, and Sleep

Summary:
In essence, wrinkles result from a complex interplay between biological aging, environmental factors, and lifestyle choices. Taking care of the skin through hydration, sun protection, a balanced diet, and adequate sleep can slow the process and keep skin looking smoother longer.